CACNB2, also known as Calcium Channel Voltage-Dependent Beta 2 Subunit, is a protein that plays a crucial role in the functioning of voltage-gated calcium channels (VGCCs). These channels are responsible for regulating calcium influx into cells in response to changes in membrane potential, thereby controlling various physiological processes such as neurotransmitter release, muscle contraction, and gene expression. One of the primary functions of CACNB2 is its role as a regulatory subunit of VGCCs. It interacts with the pore-forming alpha subunits of VGCCs, modulating their biophysical properties, including voltage sensitivity, kinetics of channel opening and closing, and calcium conductance. CACNB2 helps regulate...