Testing for D-dimer levels is beneficial for individuals suspected of having thrombotic disorders like deep vein thrombosis or pulmonary embolism. It is particularly useful in assessing the risk or presence of these conditions in patients who show symptoms of thrombosis, such as unexplained swelling, pain, or redness in the limbs, or sudden shortness of breath. However, it is not routinely used in patients with a low probability of these conditions, as D-dimer levels can be elevated due to other factors.

High D-dimer levels themselves do not cause symptoms. Instead, they are indicative of an underlying condition that may be causing blood clot formation and breakdown. The symptoms would therefore be related to the condition causing the elevated D-dimer levels, such as swelling, pain, and redness in the case of a deep vein thrombosis, or chest pain and shortness of breath in the case of a pulmonary embolism.

Lowering D-dimer levels involves treating the underlying cause of the elevated levels. This often includes managing conditions that lead to increased clot formation, such as anticoagulant therapy for thrombosis. Lifestyle changes such as regular exercise, maintaining a healthy weight, and smoking cessation can also help lower the risk of clot formation. However, it’s important to note that D-dimer levels are a symptom, not a cause, so direct reduction of D-dimer without addressing the underlying issue is not a typical medical approach.