H2BC1 refers to Histone H2B type 1-C/E/F/G/I, a member of the histone H2B family, which is essential for the packaging of DNA into chromatin within the nucleus of eukaryotic cells. Histones, including H2B proteins, play a crucial role in regulating gene expression by modulating the accessibility of DNA to transcription factors and the transcriptional machinery. H2BC1 is specifically involved in forming the core structure of nucleosomes, the basic repeating units of chromatin. Within nucleosomes, H2B proteins, along with histones H2A, H3, and H4, form an octameric complex around which DNA is wrapped. This compacted structure helps to organize and condense the...