GetTested's Genetic Methylation Mest UK dives deep into your body's methylation processes by examining key genes. This crucial biological process influences gene expression, DNA repair, and detoxification pathways, impacting everything from your energy levels to your mood and immune response. Especially beneficial for those keen on understanding their detoxification ability, facing unexplained health issues, or aiming to enhance their overall health, this test illuminates your body's methylation efficiency.

We analyze genes such as BHMT, MTHFR, COMT, and others to shed light on your methylation handling. This vital process underpins cellular health, potentially affecting your risk for certain conditions, your nutritional needs, and how you respond to environmental toxins.

About the genes in the DNA Methylation test:

• • BHMT: Contributes to the conversion of homocysteine to methionine, a key process for the body's methylation and detoxification.
  • BHMT2: Closely related to BHMT and also plays a role in the methylation process by contributing to homocysteine metabolism.
  • CHDH: Codes for choline dehydrogenase that converts choline to betaine, necessary for methylation and homocysteine clearance.
  • COMT: Responsible for the breakdown of dopamine and other catecholamines. Affects methylation and is linked to stress response and mood.
  • DHFR: Dihydrofolate reductase is involved in converting dihydrofolate to tetrahydrofolate, essential for DNA synthesis and repair.
  • ENOSF1: Associated with the metabolism of vitamin B2 and plays a role in energy production and cellular repair mechanisms.
  • FOLH1: Plays a role in converting folate to its active form, which is important for DNA synthesis and repair.
  • GNMT: Contributes to the regulation of SAM-e (S-adenosylmethionine) levels and thus the methylation balance in the body.
  • MTHFD1: Encodes an enzyme that is involved in the folate metabolism pathway, crucial for generating formate and tetrahydrofolate for DNA synthesis.
  • MTHFR: Key gene for the production of methylenetetrahydrofolate reductase, crucial for converting folate to methylfolate and the entire methylation cycle.
  • MTR: Helps convert homocysteine to methionine using folate and vitamin B12, crucial for DNA synthesis.
  • MTRR: Responsible for regenerating methylcobalamin, ensuring the continuous function of MTR in homocysteine metabolism.
  • PEMT: Important for the production of phosphatidylcholine, supporting cell membranes and methylation processes by providing choline.
  • PRXL2A: Less explored in the context of methylation, but may be involved in antioxidative defense mechanisms.
  • SHMT1: Contributes to the synthesis of serine and glycine and to folate metabolism, affecting DNA methylation and synthesis.
  • TRDMT1: Plays a role in DNA methylation, a process important for gene expression and genome stability.

How the Genetic Methylation Test Works

Ordering and completing the DNA Methylation test is straightforward:

• • 1. Order the Test: Get your DNA Methylation test kit delivered directly to your home.
    2. Collect Your Sample: Follow the simple instructions to collect your saliva sample.
    3. Send It Back: Use the prepaid return envelope to send your sample to our laboratory.
    4. Receive Your Results: Within 6-8 weeks, you will receive a detailed digital report, highlighting your methylation pathways with personalized recommendations.

Why Opt for DNA Methylation Testing?

Understanding your methylation status opens the door to tailored dietary and lifestyle adjustments, potentially revealing hidden health issues or optimizing your wellness strategy. This test suits anyone curious about their genetic health, seeking to tailor their lifestyle to their genetics, or dealing with unexplained health challenges.

Sample and Privacy

We ensure the privacy of your DNA and sample by destroying them post-analysis, linking them only to your unique test ID for complete anonymity. The laboratory will not know whom it belongs to, and we do not share the results with any third party. You also have the option to delete your test results after receiving them.